Resveratrol Liposomal (250mg x 5ml) - 250ml (50 doses)

Powerful antioxidant for cell protection

Liposomal resveratrol acts as a potent antioxidant, helping to neutralize free radicals that contribute to cellular aging and tissue deterioration. Its ability to reduce oxidative stress protects DNA, cell membranes, and mitochondria from cumulative damage caused by environmental factors and metabolic processes. This action contributes to greater cellular longevity and the maintenance of a more resilient organism in the face of the effects of time.

Cardiovascular health support

Resveratrol plays a key role in protecting the cardiovascular system by improving endothelial function and promoting optimal blood circulation. Its ability to modulate nitric oxide production contributes to the relaxation of blood vessels, promoting better arterial elasticity and reducing blood pressure in people with high levels. Furthermore, it helps balance LDL cholesterol and triglyceride levels, reducing the risk of atherosclerosis and cardiovascular complications.

Activator of sirtuins and cellular longevity

Resveratrol is known for its ability to activate sirtuins, a group of regulatory proteins that play an essential role in DNA repair, mitochondrial efficiency, and the cellular stress response. Its influence on these processes makes it a key compound in strategies focused on healthy aging and extending cell lifespan. By optimizing metabolic functions and protecting against genetic damage, it contributes to greater resilience against age-related decline.

Improved mitochondrial function and energy production

Mitochondria are the powerhouses of cells, and their proper functioning is essential for maintaining high energy levels and efficient metabolism. Liposomal resveratrol stimulates mitochondrial biogenesis and promotes the production of ATP, the cell's primary fuel. This results in increased physical and mental vitality, with noticeable benefits in endurance, muscle recovery, and cognitive clarity.

Regulation of metabolism and control of inflammation

Resveratrol has been shown to have a positive impact on metabolic regulation by improving insulin sensitivity and promoting a balance in glucose and lipid metabolism. Its anti-inflammatory action helps reduce chronic low-grade inflammation, a factor associated with various metabolic and degenerative diseases. These effects may contribute to better weight management, a reduced risk of insulin resistance, and greater stability in energy levels throughout the day.

Neurocognitive protection and support for brain function

The antioxidant and anti-inflammatory action of liposomal resveratrol benefits neuronal health by reducing oxidative damage and improving communication between brain cells. Its influence on synaptic plasticity and cerebral blood flow supports memory, learning, and mental clarity. Furthermore, its ability to modulate neuroinflammation and protect against the accumulation of amyloid plaques makes it a compound of interest in preventing age-related cognitive decline.

Support for the health of the skin and connective tissues

Resveratrol contributes to cell regeneration and collagen synthesis, helping to maintain the skin's elasticity, hydration, and firmness. Its protective effect against damage induced by UV radiation and environmental pollution makes it an ally in preventing premature skin aging. Furthermore, its action on connective tissues can benefit joint health and the repair of structures affected by mechanical stress or inflammation.

Optimization of bioavailability and prolonged efficacy

The liposomal formulation of resveratrol significantly improves its absorption and stability in the body, overcoming the bioavailability limitations of its conventional form. Thanks to this technology, the compound is transported more efficiently to cells, allowing for a longer and more effective action at lower doses. This maximizes therapeutic benefits without the need for repeated administrations or combinations with other potentiating agents.

Activation of sirtuins and regulation of cellular longevity

Resveratrol is an activator of the sirtuin protein family, particularly SIRT1, which plays a key role in regulating cellular metabolism and longevity. Sirtuins are NAD+-dependent enzymes that modulate gene expression by deacetylating histones and regulatory proteins. This mechanism contributes to genomic stability, DNA repair, and optimized mitochondrial function—fundamental processes in preserving cellular health and reducing the effects of aging. SIRT1 activation also regulates the response to caloric restriction, which can influence lifespan extension and improve metabolic efficiency.

Modulation of oxidative stress and action as an antioxidant

Resveratrol acts as a potent free radical scavenger thanks to its polyphenolic structure, which allows it to donate electrons and neutralize reactive oxygen species (ROS). In addition to its direct action on oxidative stress, resveratrol regulates the expression of antioxidant genes through the activation of the Nrf2 pathway (nuclear erythroid factor 2-related factor 2). This mechanism induces the transcription of endogenous antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), increasing the body's ability to counteract oxidative damage and maintain cellular homeostasis.

Improved mitochondrial function and energy biogenesis

Resveratrol stimulates mitochondrial biogenesis by activating PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1α), a master regulator of new mitochondrial production and energy metabolism. By improving mitochondrial efficiency, resveratrol increases ATP production through oxidative phosphorylation, thus optimizing cellular energy capacity. Furthermore, its action on the electron transport chain reduces the production of reactive oxygen species within the mitochondria, minimizing oxidative damage and promoting long-term cellular function.

Regulation of inflammation and modulation of the NF-κB pathway

Resveratrol has anti-inflammatory effects through the inhibition of the NF-κB (nuclear factor kappa B) pathway, a protein complex that regulates the expression of pro-inflammatory genes. Chronic activation of NF-κB is implicated in various inflammatory and degenerative diseases, making its modulation key in reducing low-grade systemic inflammation. Furthermore, resveratrol suppresses the production of inflammatory cytokines such as TNF-α, IL-6, and IL-1β, regulating the immune response and contributing to the homeostasis of the inflammatory system.

Effect on endothelial function and cardiovascular regulation

Resveratrol improves vascular health by activating the enzyme eNOS (endothelial nitric oxide synthase), which catalyzes the production of nitric oxide (NO), a key vasodilator in regulating vascular tone. Increased NO bioavailability promotes blood vessel relaxation, improves arterial elasticity, and reduces blood pressure. Furthermore, its effect on reducing oxidative stress and inflammation in the endothelium prevents vascular dysfunction and the progression of atherosclerosis.

Neuroprotection and optimization of cognitive function

Resveratrol crosses the blood-brain barrier and exerts neuroprotective effects by modulating various pathways related to brain function. Its antioxidant and anti-inflammatory action reduces neuronal damage caused by oxidative stress and the accumulation of neurotoxic proteins. It also improves synaptic plasticity by stimulating BDNF (brain-derived neurotrophic factor), promoting the formation and maintenance of new neuronal connections. This mechanism is key in preventing cognitive decline and supporting memory and learning.

Regulation of glucose and insulin metabolism

Resveratrol improves insulin sensitivity and modulates glucose metabolism by activating the AMPK (AMP-activated protein kinase) pathway, a central metabolic regulator that optimizes glucose uptake in peripheral tissues and improves energy production efficiency. AMPK activation reduces lipid accumulation in the liver and decreases insulin resistance, key factors in preventing metabolic disorders such as type 2 diabetes.

Inhibition of uncontrolled cell proliferation

Resveratrol regulates cell proliferation and apoptosis by modulating various cell cycle regulatory proteins, such as p53 and Bax. Its ability to induce apoptosis in damaged or dysfunctional cells is a key mechanism in preserving cell integrity and preventing the accumulation of cells with genetic mutations. Furthermore, its effect on DNA methylation and the expression of genes involved in cell division contributes to genome stability and the reduction of long-term cell damage.

Skin protection and collagen synthesis

Resveratrol contributes to skin regeneration and maintenance by activating pathways that regulate collagen synthesis and reducing UV-induced damage. Its antioxidant action prevents the degradation of collagen and elastin, proteins essential for skin firmness and elasticity. It also modulates the activity of enzymes such as matrix metalloproteinases (MMPs), which are involved in the deterioration of the extracellular matrix, helping to preserve dermal structure and prevent premature aging.

Optimizing cellular longevity

Dosage:
Initial dose: 5 ml per day
Therapeutic dose: 10 ml per day (5 ml in the morning and 5 ml in the afternoon)
Maintenance dose: 5 ml per day

Administration frequency:
Take on an empty stomach to improve absorption and maximize bioavailability. The first dose in the morning supports sirtuin activation and cellular metabolism, while a second dose in the afternoon provides continuous support for cellular repair and antioxidant protection.

Total cycle duration:
A 12-week cycle followed by a 1-week break. It is recommended to continue the protocol to maintain long-term benefits.

Cardiovascular protection and vascular health

Dosage:
Initial dose: 5 ml per day
Therapeutic dose: 10 ml per day (5 ml in the morning and 5 ml in the afternoon)
Maintenance dose: 5 ml per day

Administration frequency:
Take on an empty stomach or with a meal rich in healthy fats to improve absorption. Morning administration helps regulate blood pressure and endothelial function throughout the day.

Total cycle duration:
A 14-week cycle followed by 2 weeks of rest. This can be repeated continuously to maintain cardiovascular protection.

Cognitive support and neuroprotection

Dosage:
Initial dose: 5 ml per day
Therapeutic dose: 10 ml per day (5 ml in the morning and 5 ml in the afternoon)
Maintenance dose: 5 ml per day

Administration frequency:
Take on an empty stomach in the morning to enhance cognitive function, memory, and neuronal plasticity throughout the day. A second dose in the afternoon can help maintain mental focus without interfering with nighttime sleep.

Total cycle duration:
A 10-week cycle followed by a 1-week break. It can be resumed continuously to maintain neuroprotective benefits.

Metabolic regulation and inflammation control

Dosage:
Initial dose: 5 ml per day
Therapeutic dose: 10 ml per day (5 ml in the morning and 5 ml in the afternoon)
Maintenance dose: 5 ml per day

Administration frequency:
Take on an empty stomach in the morning to improve insulin sensitivity and metabolic homeostasis. The second dose in the afternoon helps maintain inflammatory regulation for the rest of the day.

Total cycle duration:
A 12-week cycle followed by 2 weeks of rest. It can be maintained for an extended period as needed.

Support for the health of the skin and connective tissues

Dosage:
Initial dose: 5 ml per day
Therapeutic dose: 10 ml per day (5 ml in the morning and 5 ml in the afternoon)
Maintenance dose: 5 ml per day

Administration frequency:
Take on an empty stomach or with a healthy source of fat to improve absorption. Taking it in the morning promotes collagen synthesis and protection against oxidative damage, while taking it in the afternoon aids in nighttime cell repair.

Total cycle duration:
A 14-week cycle followed by a 1-week break. It can be resumed to maintain skin elasticity and firmness.

Enhancement of mitochondrial function and energy production

Dosage:
Initial dose: 5 ml per day
Therapeutic dose: 10 ml per day (5 ml in the morning and 5 ml in the afternoon)
Maintenance dose: 5 ml per day

Administration frequency:
Take on an empty stomach in the morning to promote mitochondrial biogenesis and efficient ATP production. The second dose in the afternoon provides continuous support for energy metabolism without causing fatigue.

Total cycle duration:
A 10-week cycle followed by 2 weeks of rest. It can be continued long-term to maintain optimal energy levels.

Bioavailability and absorption

• Piperine (Pepper Extract): Increases the absorption of Resveratrol by inhibiting its rapid elimination, allowing for a longer stay in the body.
• C15 (Pentadecanoic Acid): Improves the absorption and distribution of Resveratrol in tissues, optimizing its antioxidant and anti-inflammatory action.

Activation of sirtuins and cellular longevity

• NMN (Nicotinamide Mononucleotide): Enhances the activation of SIRT1 by raising NAD+ levels, essential for the function of Resveratrol in cellular longevity.
• Coenzyme Q10: Strengthens energy production and protects mitochondria, complementing the action of Resveratrol in mitochondrial biogenesis.

Cardiovascular protection and endothelial function

• Vitamin K2 (MK4 and MK7): Regulates calcium metabolism and improves arterial health, reducing the risk of vascular calcification.

Neuroprotection and cognitive optimization

• Longevicell (Ergothioneine + Shiitake extract): Protects the brain from oxidative stress and complements the neuroprotective action of Resveratrol.
• Liposomal astaxanthin: Reduces brain inflammation and improves blood flow to the central nervous system.

Modulation of inflammation and cellular metabolism

• Apigenin: Regulates the inflammatory response and reduces the impact of oxidative stress, working in synergy with Resveratrol.
• Ellagic Acid: Supports cellular detoxification and protects DNA from oxidative damage.

Skin and connective tissue health

• Hyaluronic Acid: Promotes cellular hydration and improves skin elasticity.
• Bone broth: Strengthens the regeneration of connective tissues and promotes skin firmness.

What is Liposomal Resveratrol?

Liposomal resveratrol is an advanced form of resveratrol designed to improve its absorption and bioavailability in the body. Unlike conventional resveratrol, which has low solubility and is rapidly metabolized, liposomal technology encapsulates the compound in phospholipids, allowing it to cross cell membranes more efficiently. This ensures prolonged action and greater effectiveness in its antioxidant, anti-inflammatory, and sirtuin-activating functions.

What is liposomal resveratrol used for?

Liposomal resveratrol offers numerous benefits, from protecting cells against oxidative stress to regulating key metabolic processes. Its ability to activate sirtuins makes it an ally in cellular longevity, while its anti-inflammatory action helps prevent chronic diseases. It also supports cardiovascular health by improving arterial elasticity and reducing LDL cholesterol oxidation.

What is the difference between conventional resveratrol and liposomal resveratrol?

Conventional resveratrol has limited absorption and is rapidly metabolized in the liver, reducing its effectiveness. In contrast, liposomal resveratrol is encapsulated in phospholipids, allowing for better intestinal absorption and more efficient distribution to tissues. This improves its bioavailability and prolongs its presence in the body, making its effects more pronounced and longer-lasting.

How does resveratrol work in the body?

Resveratrol acts by modulating various metabolic and cellular pathways. Its most prominent mechanism is the activation of sirtuins, proteins that regulate cellular longevity and mitochondrial function. It also reduces inflammation by inhibiting the NF-κB pathway and protects against oxidative damage by increasing the expression of antioxidant genes. Furthermore, it improves cardiovascular function by stimulating nitric oxide production, promoting vasodilation and blood flow.

How long does it take for Liposomal Resveratrol to take effect?

The effects of resveratrol can vary depending on metabolism and consistency of use. In the short term, many people experience improved energy and mental clarity within the first few weeks. Cardiovascular and antioxidant benefits require continuous use for at least 8 to 12 weeks, while the effects on cellular longevity are enhanced with prolonged use.

What is the recommended dose of Liposomal Resveratrol?

The recommended dosage varies depending on the intended use. Generally, 5 ml per day is recommended for maintenance, and 10 ml per day for therapeutic protocols. It is recommended to take it on an empty stomach to maximize absorption.

Is it better to take liposomal resveratrol with or without food?

For optimal absorption, liposomal resveratrol should be taken on an empty stomach. However, to improve its solubility, it can be taken with a meal rich in healthy fats, such as avocado or nuts. This can improve its stability in the body without affecting its bioavailability.

How long should Liposomal Resveratrol be taken?

Liposomal resveratrol can be taken continuously, as it is a natural and safe compound. To maximize its benefits, a 12- to 16-week cycle followed by a 1- to 2-week break before resuming use is recommended.

Does resveratrol help with longevity?

Resveratrol is one of the most studied compounds in the field of cellular longevity. Its ability to activate SIRT1 and improve mitochondrial function is associated with extending cell lifespan and optimizing age-related metabolic processes. However, its effect on human longevity depends on multiple factors, such as diet and lifestyle.

Is resveratrol an antioxidant?

Yes, resveratrol is a powerful antioxidant that neutralizes free radicals and protects cells from oxidative damage. Its antioxidant action is also enhanced by activating the Nrf2 pathway, increasing the production of endogenous enzymes such as superoxide dismutase and catalase, which protect against oxidative stress.

Does resveratrol improve cardiovascular health?

Yes, resveratrol has a positive impact on cardiovascular health by improving endothelial function and blood circulation. It stimulates nitric oxide production, promoting vasodilation and reducing blood pressure. It also protects against LDL cholesterol oxidation, reducing the risk of atherosclerosis.

Is resveratrol helpful for memory and cognitive function?

Resveratrol has neuroprotective effects, as it reduces brain inflammation and improves blood flow to the brain. It also stimulates the production of BDNF, a key factor in neuronal plasticity and the formation of new synaptic connections. These effects can improve long-term memory, learning, and mental clarity.

Does resveratrol help reduce inflammation?

Yes, resveratrol modulates the inflammatory response by inhibiting the NF-κB pathway, reducing the production of pro-inflammatory cytokines such as IL-6 and TNF-α. This mechanism helps reduce chronic inflammation, which is linked to various metabolic and neurodegenerative diseases.

Can resveratrol help regulate metabolism?

Resveratrol improves insulin sensitivity and glucose uptake in cells by activating the AMPK pathway. It also reduces liver fat accumulation and enhances lipid oxidation, which can be beneficial in regulating metabolism and body composition.

Does resveratrol protect against cell damage?

Yes, resveratrol protects cells against oxidative damage, inflammation, and mitochondrial dysfunction. It also plays a role in DNA stability and cell cycle regulation, helping to preserve cellular integrity over time.

Does resveratrol help with skin health?

Resveratrol contributes to cell regeneration and collagen production, improving skin elasticity and firmness. It also protects against damage caused by UV radiation and pollution, helping to prevent premature aging.

Does resveratrol have side effects?

Resveratrol is generally well-tolerated at appropriate doses, but in some people it can cause mild digestive discomfort or headaches if taken at very high doses. In rare cases, it may interact with certain blood-thinning medications.

Can Resveratrol be combined with other supplements?

Yes, resveratrol is frequently combined with NMN, coenzyme Q10, astaxanthin, and piperine to enhance its effectiveness. It can also be supplemented with antioxidants such as vitamin C to boost its protective action.

Is resveratrol safe for long-term use?

Yes, resveratrol is a natural compound that can be consumed continuously. However, it is recommended to follow a cycling protocol to optimize its effectiveness and avoid any possible adaptation by the body.

Is liposomal resveratrol better than resveratrol in capsules or powder?

Yes, liposomal resveratrol has significantly greater absorption and bioavailability than resveratrol in capsules or powder. Encapsulation in liposomes allows the compound to cross cell membranes more efficiently and prevents its rapid degradation in the liver. This means that lower doses are required to obtain the same or even greater benefits compared to conventional forms of resveratrol.

Does liposomal resveratrol affect blood pressure?

Resveratrol has a positive effect on blood pressure by promoting nitric oxide production, which improves blood vessel dilation and reduces vascular resistance. In people with high blood pressure, it can contribute to a moderate reduction in blood pressure readings, but in those with low blood pressure, its effect can be more variable. Monitoring changes is recommended for individuals with pre-existing conditions.

Can resveratrol replace a healthy diet?

No, resveratrol is a supplement that enhances the effects of a healthy lifestyle, but it doesn't replace a balanced diet or other essential habits like exercise and adequate rest. To maximize its benefits, it should be integrated into a comprehensive approach that includes a diet rich in antioxidants, healthy fats, and quality protein.

Can resveratrol help lower cholesterol?

Yes, resveratrol can reduce the oxidation of LDL cholesterol, which helps prevent plaque buildup in the arteries. It can also influence the regulation of blood lipid levels by improving insulin sensitivity and metabolic function, although its effect is most noticeable when combined with other healthy habits such as a proper diet and regular physical activity.

Is it advisable to take Resveratrol if you are following a ketogenic or intermittent fasting diet?

Yes, resveratrol is compatible with a ketogenic diet or intermittent fasting. In fact, its activation of the AMPK pathway and sirtuins makes it an excellent supplement to enhance the benefits of fasting and ketosis. It can help optimize autophagy, improve mitochondrial function, and boost the anti-inflammatory effects of fasting.

Does resveratrol improve recovery after exercise?

Resveratrol can aid in muscle recovery thanks to its antioxidant and anti-inflammatory effects. It reduces oxidative damage induced by intense exercise and helps preserve mitochondrial function, promoting better energy production and faster recovery. It can also modulate post-workout inflammation, reducing muscle soreness.

Can resveratrol improve sleep quality?

Although resveratrol is not a specific sleep supplement, its action in regulating oxidative stress and inflammation may indirectly contribute to better sleep quality. It also has a mild modulating effect on melatonin production, which could promote a more balanced circadian rhythm when consumed regularly.

Does resveratrol have any impact on gut health?

Yes, resveratrol has prebiotic and anti-inflammatory properties that can benefit the gut microbiota. Studies suggest it may promote the growth of beneficial bacteria and reduce inflammation in the digestive tract. It has also been observed to modulate the integrity of the intestinal barrier, helping to prevent intestinal permeability.

Is resveratrol safe for people with diabetes?

Resveratrol may be beneficial for people with type 2 diabetes, as it improves insulin sensitivity and regulates glucose uptake in cells. Its activation of the AMPK pathway promotes more efficient energy metabolism and may contribute to glycemic control. However, if diabetes medication is being taken, it is recommended to adjust its intake according to individual response.

Can liposomal resveratrol reduce the risk of neurodegenerative diseases?

Resveratrol has demonstrated neuroprotective effects by reducing oxidative stress, brain inflammation, and the accumulation of amyloid plaques in the brain. These mechanisms make it a compound of interest in the prevention of cognitive decline and diseases such as Alzheimer's and Parkinson's. Although it is not a cure, its long-term use may contribute to maintaining optimal brain function.

Does resveratrol have any effect on collagen production?

Yes, resveratrol can stimulate collagen production and protect against its degradation by reducing the activity of enzymes that break down the extracellular matrix. This makes it an ally for the health of skin, joints, and connective tissues, promoting a firmer appearance and improved cell regeneration.

Is it safe to take resveratrol long-term?

Yes, resveratrol is safe for long-term use when consumed in appropriate doses. Its mechanism of action is based on the modulation of beneficial cellular processes, so it can be taken continuously in strategic cycles to optimize its effectiveness.

Is resveratrol suitable for all ages?

Resveratrol is generally safe for adults, but its use in children or adolescents is not well studied. In older adults, it may be particularly beneficial due to its impact on cellular longevity and protection against accelerated aging.

Does resveratrol affect liver function?

Resveratrol has hepatoprotective properties and may help reduce liver inflammation in people with fatty liver disease or high oxidative stress. However, at extremely high doses, it could alter some liver enzymes, so it is recommended to follow the recommended dosages.

Can resveratrol help improve mood?

Resveratrol has a positive impact on dopaminergic and serotonergic function, which can influence mood stability and stress response. It can also reduce neuroinflammation, which in turn supports mental health and emotional well-being.

Is it better to take Resveratrol in the morning or at night?

Resveratrol is recommended to be taken in the morning or afternoon on an empty stomach to maximize absorption. Avoid taking it at night, as some users report a slight increase in energy that could disrupt sleep.

Does resveratrol interact with other supplements?

Resveratrol can be combined with other supplements such as NMN, Coenzyme Q10, Piperine, and Astaxanthin to enhance its effects. However, its combination with anticoagulants or certain medications should be monitored, as it can affect blood clotting.

Does resveratrol have an effect on mitochondrial function?

Yes, resveratrol stimulates mitochondrial biogenesis by activating PGC-1α and improving cellular energy efficiency. This promotes increased ATP production and reduces cellular fatigue associated with aging or metabolic stress.

Can resveratrol reduce the damage caused by stress?

Resveratrol helps modulate the stress response by reducing systemic inflammation and improving cellular resilience. Its activation of sirtuins also contributes to the regulation of energy metabolism, which can promote better adaptation to prolonged stress.

How is liposomal resveratrol stored?

To maintain its stability, liposomal resveratrol should be stored in a cool, dry place, away from light and heat. Once opened, refrigeration is recommended to preserve its integrity and prevent oxidation of the compound.